Over the past three decades, the study found that most of these countries have experienced significant declines in midlife mortality from all possible causes of death, known as all-cause mortality. As a result, by 2019, the US saw all-cause mortality rates that were 2.5 times higher than the average of other high-income countries studied. Worsening midlife mortality in the US was driven by several causes of death, including highly preventable ones such as transport accidents, homicide, suicide and drug overdoses. Study figure: Percentage change in all-cause mortality rates since 1990. International trends in midlife mortality', appears in the International Journal of Epidemiology.