Post-doc position in Computational Systems Biology

The Department of Developmental BioEngineering at the University of Twente (Enschede, the Netherlands) is looking for a computational modeler to describe and predict factors for better stem cell differentiation for heart tissue engineering applications. This project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the University of Twente.

Current animal and cell culture models are not accurate enough to predict the efficacy and toxicity of drugs. In this research project, titled ‘ Advanced bioengineering strategy for production of human miniature hearts' , a multidisciplinary team consisting of (developmental) biologists, bioinformaticians, and mathematicians will encapsulate human stem cells in hollow miniature spheres made from hydrogel and use single cell OMICs analysis to make digital twins of the miniature hearts. The digital twins generated in this project allow investigating heart development and predicting the response of the heart to medication.

Your profile

We look for a highly motivated, enthusiastic researcher who is driven by curiosity and:

Has, or will shortly acquire, a PhD degree in (Applied) Mathematics, Systems Biology, Biomedical Engineering, or a related field;

Has experience with mathematical modelling and analysis with large-scale simulation tools and/or bifurcation analysis;

Has experience with (mathematical) programming languages, e.g. Python, R, Matlab, etc.

Has a strong interest in systems biology;

Experience with analysis of big data (transcriptomics, proteomics) and / or heart development will be considered a benefit;

Is a team player with good communication skills;

Has demonstrated scientific creativity that has preferably resulted in recent and relevant high- quality scientific publications in international journals

Is proficient in English, both spoken and written.

Has an interest in contributing to the education of Ba-Ma students

Experience in managing projects and writing project proposals will be considered a benefit.

Our offer

We offer an inspiring and challenging multidisciplinary and international environment. You will be initially employed for 45 months. The terms of employment are in accordance with the Dutch Collective Labour Agreement for Universities (CAO) and include:

A fulltime Post-Doc position for 45 months;

Full status as an employee at the UT, including pension and health care benefits;

Gross monthly salary between € 3,413 and € 4,670.- (depending on experience and qualifications)

The University of Twente provides excellent facilities for professional and personal development, a holiday allowance and an end-of-year bonus;

A solid pension scheme;

A lively and green campus with many facilities for sports and other extracurricular activities;

Excellent facilities for professional and personal development.

Your main responsibility will be to carry out research, but you will be given the opportunity to acquire some teaching experience and supervise students in Master and Bachelor projects as well.

Total of 41 holiday days in case of full-time employment

Information and application

Are you interested to be part of our team? Please send your application and include:

A motivation letter explaining your interest and qualifications for this position;

A detailed CV (resume) with a publication list;

The name and e-mail address/telephone number of two references;

A copy of your PhD-thesis and two of your related scientific papers;

We may request a TOEFL or IELTS score to verify sufficient skills in English.

For inquiries about this position and our offer you can contact Janine Post, PhD ([email protected]). An application for this position should be accompanied by motivation and curriculum vitae, including a list of publications (when applicable) and can be submitted via the button below or website

About the department

Department of Developmental BioEngineering The department of Developmental BioEngineering is a research group with a highly international character. The main goal of this group is to investigate novel and challenging technologies in the field of Regenerative Medicine, which can be used for tissue repair. Research focuses on i) Fundamental aspects of joint and cartilage homeostasis, ii) Cell therapy for treatment of joint disorders, and iii) Injectable, in situ gelating extracellular matrices for soft tissue repair, iv) computational models for tissue development and homeostasis. DBE The project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the same university (UT). This department focuses on topics in the area of dynamical systems, numerical analysis and scientific computing, and systems and control, and in particular, their relation with data science. EEMCS

About the organisation

The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.

Want to know more? Post, J.N. (Janine)

Associate Professor

Post, J.N. (Janine)

Associate Professor

Do you have questions about this vacancy? Then you can contact Janine for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.

Contact

Phone:+31534894205

Email:[email protected]

How to apply Step 1

Apply. When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.

Step 2

Selection. The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.

Step 3

1st interview. The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.

Step 4

2nd interview. In the second interview, we will further discuss the job content, your skills and your talents.

Step 5

The offer. If the conversations are positive, you will be made a suitable offer.

Your Colleagues

Steenbergen, W. (Wiendelt)

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Pizzoccaro - Zilamy, M.D. (Marie-Alix)

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Vargas Llona, L.D. (Laura)

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Our university is a public institution that serves society. We are accountable to society for the ways in which we use our academic freedom. We are responsible for ensuring that the power of science and technology is harnessed to achieve the best possible impact in a changing world. We cherish our rich tradition of combining technical and social sciences in our five profiling themes: Improving healthcare by personalized technologies; Creating intelligent manufacturing systems; Shaping our world with smart materials; Engineering our digital society; and Engineering for a resilient world.

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