Department: DKTK partner site Munich, Department of Medicine III (University Hospital of Munich, LMU, Spiekermann lab) and the Core Facility "Mouse Models of Acute Leukemias" (HMGU / Jeremias lab)
Code number: 2023-0058
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).
At the DKTK partner site Munich the Department of Medicine III (University Hospital of Munich, LMU, Spiekermann lab) and the Core Facility "Mouse Models of Acute Leukemias" (Helmholtz Munich / Jeremias lab) are offering a PhD position as part of the programs „Molecular Diagnostics, Early Detection and Biomarker Development“ and „Exploitation of Oncogenic Mechanisms“.
Therapy resistance is a major problem in cancer therapy resulting in cancer recurrence and finally therapy failure. This translational project focusses on acquired mechanisms of resistance towards targeted agents in acute leukemias with a focus on Antibody Drug Conjugates (ADC). Multi-omics characterization of in vitro and in vivo models of drug resistance will be used to identify candidates for functional characterization. Moreover, clinical samples will be characterized to validate findings from model systems in human disease.
The project will require approximately 50% wet lab und 50% dry lab work.
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ.
Earliest Possible Start Date: as soon as possible
Duration: The position is limited to 3 years.
Application Deadline: 14.03.2023
Christine Koppenhöhl Phone +49 (0)89/4400-54627
Please note that we do not accept applications submitted via email.
The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.
Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.
To apply for a position please use our online application portal (https: // www. dkfz.de/en/stellenangebote/index.php).
We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.