PhD position on a Virtual Bone Morphology Processing Platform for Orthopedic Applications

University of Twente
March 29, 2024
Offerd Salary:€ 2.770
Working address:N/A
Contract Type:Other
Working Time:Full time
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Knowledge about the individual bone morphology plays a key role in the new generation of innovative personalized biomedical products and treatments. Bone morphology can be used to answer research questions, such as quantifying the progression of degenerative diseases; analyzing gender, age, and ethnic differences within a population; or building a digital twin model to aid in anatomic reconstruction, and direct design applications of implants and prostheses. Despite the need, such data are rarely available. The reasons are manifold: the access to large numbers of medical image data is limited, implementation of image processing strategies is challenging, data are collected only for isolated questions or applications, and legal uncertainties play a role with respect to privacy and conflicting economic interests. In addition, knowledge from a variety of disciplines is required.


The PhD's objective is to develop the contours and pilot work of an open- access virtual processing platform for uploading, processing, enriching, and storing medical image data in order to provide a large number of fully processed bone morphology data to various research communities. Thereto, an overview is made of running initiatives; and pros and cons are evaluated. Optionally, we will team up with these initiatives. The PhD develops robust (semi-) automatic segmentation and processing methods applicable to different bony structures. We demonstrate the benefit and potential of such a virtual platform by selected use cases in the orthopaedic domain, e.g. joint replacement. Our ambition is to evolve the PhD candidate's work into an open- access and sustainable platform, which can be operated and used in the long term to provide and enable for future research.

Your profile
  • You have, or will shortly acquire, a master's degree in Computer science, Software Engineering, Medical Informatics, Electrical Engineering, Vision Robotics, or equivalent
  • You have profound knowledge and skills in medical image segmentation, image processing, and statistical shape modelling
  • You have excellent experience in software design and (MATLAB & Python) programming
  • You have affinity with medical applications and device design and are willing to dive deeper into these topics
  • You have good team spirit and like to work in an interdisciplinary and internationally oriented environment
  • You are fluent in English, both spoken and written, and have strong analytical and organizational skills
  • Our offer

    We offer a very stimulating position in a dynamic and international environment with enthusiastic colleagues, excellent working conditions and a green and lively campus.

  • A fully funded full-time 4-year PhD position;
  • Excellent mentorship and a stimulating international research environment;
  • A training program as part of the Twente Graduate School where you and your supervisors will determine a plan for a suitable education and supervision;
  • A gross monthly salary ranging from € 2.770,- (first year) to € 3.539,- (fourth year)
  • A holiday allowance of 8% of the gross annual salary and a year-end bonus of 8.3%;
  • The flexibility to work (partially) from home;
  • Minimum of 29 holidays per year in case of fulltime employment;
  • Free access to sports facilities on campus;
  • We encourage a high degree of responsibility and independence, while collaborating with close colleagues, researchers and other staff.
  • Female applicants are explicitly asked to apply for this position. This is part of the University of Twente's strategy to increase the proportion of women among its faculty and to create a working environment that is diverse and inclusive and supportive of excellence in research and teaching.

    Information and application

    You are welcome to contact Dr.-Ing. Malte Asseln ([email protected]) or Gabrielle Tuijthof ([email protected]) for any questions you might have.

    Please submit your application before March 29th 2024 by using the “Apply now” button and include the following documents:

  • A motivation letter, emphasizing your specific interest and motivation to apply for this PhD position in our group.
  • A full Curriculum Vitae including your education, publications, awards, and working experience. Your CV should demonstrate the scope of your work and education and indicate a good fit with the stated requirements for the position.
  • An academic transcript of BSc and MSc education, including grades.
  • A short description of your most recent accomplishment (master's thesis, final project report, etc.).
  • References (contact information) of two scientific staff members (such as the supervisor of your master thesis/final project) who are willing to provide a recommendation letter at our request.
  • Interviews will take place in two phases. If selected, there will be a first online interview in April. A subset of the candidates will be invited for a second (if possible in-person) interview shortly thereafter.

    About the organisation

    The Faculty of Engineering Technology (ET) engages in education and research of Mechanical Engineering, Civil Engineering and Industrial Design Engineering. We enable society and industry to innovate and create value using efficient, solid and sustainable technology. We are part of a ‘people-first' university of technology, taking our place as an internationally leading center for smart production, processes and devices in five domains: Health Technology, Maintenance, Smart Regions, Smart Industry and Sustainable Resources. Our faculty is home to about 2,900 Bachelor's and Master's students, 550 employees and 150 PhD candidates. Our educational and research programmes are closely connected with UT research institutes Mesa+ Institute, TechMed Center and Digital Society Institute.

    Want to know more Asseln, M. (Malte)

    Assistant Professor

    Asseln, M. (Malte)

    Assistant Professor

    Do you have questions about this vacancy? Then you can contact Malte for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.



    Email:[email protected]

    How to apply Step 1

    Apply. When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.

    Step 2

    Selection. The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.

    Step 3

    1st interview. The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.

    Step 4

    2nd interview. In the second interview, we will further discuss the job content, your skills and your talents.

    Step 5

    The offer. If the conversations are positive, you will be made a suitable offer.

    Your Colleagues
  • Asseln, M. (Malte)
  • Personal page

  • Tuijthof, G.J.M. (Gabriëlle)
  • Personal page

  • Verdonschot, N.J.J. (Nico)
  • Personal page

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