Advance understanding of onset and spread of Parkinson's disease using innovative cell studies and advanced microscopy; join our multidisciplinary team at the University of Twente, The Netherlands for an exciting project. Ideal candidates have a Master's in Biomedical Engineering, Molecular Biology or a related field, with a passion for biomolecule research and an interest in innovative microscopy.
Join the NBP group, a multidisciplinary team at the University of Twente, where physics, chemistry, biology, and medicine converge. We are dedicated to understanding intrinsically disordered proteins (IDPs) and their roles in biological processes. Our focus is on the study of IDPs in the context of Parkinson's disease, using advanced microscopy and spectroscopy techniques. We offer a collaborative, supportive, and professional working environment, encouraging interactions among our diverse team members, including PhD students, research technicians, and principal investigators.
Parkinson's disease (PD), often associated with a-synuclein (aS) pathology, is not typically familial, suggesting non-genetic factors in its development. Epidemiological studies hint at external factors like virus infections and exposure to certain chemicals as potential risks. However, the molecular mechanisms behind these correlations remain elusive.
This project seeks to establish a molecular link between risk factors and the initiation of aS aggregation and the spread of the pathology from cell to cell in neuronal cell models. Building on recent discoveries, we aim to explore how a singular event, such as exposure to virus proteins, can trigger aS aggregation. Using cutting-edge microscopy and spectroscopy, we will investigate this initial trigger and its cascading effects, potentially offering new insights into PD development and intervention strategies.
Your profileWe are looking for a candidate with a Master's degree in Biomedical Engineering, Molecular Biology, Biochemistry, or a related field. The ideal candidate should have:
Are you interested in this position? Please send your application via the 'Apply now' button below before 5 April 2024, and include:
For more information regarding this position, you are welcome to contact Mireille Claessens
About the organisationThe Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.
Want to know more? Claessens, M.M.A.E. (Mireille)Chair Nanobiophysics
Claessens, M.M.A.E. (Mireille)Chair Nanobiophysics
Do you have questions about this vacancy? Then you can contact Mireille for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.
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How to apply Step 1Apply. When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.
Step 2Selection. The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.
Step 31st interview. The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.
Step 42nd interview. In the second interview, we will further discuss the job content, your skills and your talents.
Step 5The offer. If the conversations are positive, you will be made a suitable offer.
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