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PhD in device engineering for efficient microhistology 100%, Zurich, fixed-termprint Drucken
The Macromolecular Engineering Laboratory within the Department of Mechanical and Process Engineering (D-MAVT) at ETH Zurich in Zurich, Switzerland, engineers and applies advanced polymeric materials for a range of biomedical and industrial uses. The recent focus of the group (www. macro.ethz.ch/) includes the development of biomedical materials and bioengineered devices for a range of applications. The lab is composed of a highly interdisciplinary and international team of motivated researchers. We are currently seeking a doctoral candidate for prototyping a design for the manipulation of microtissues, including acoustic manipulation. The position will be a part of a BRIDGE Discovery grant (in collaboration with CSEM and ZHAW).
Project backgroundMicrotissues, including organoids and spheroids, are transforming biological research, drug discovery, and personalized medicine. Histological analysis of microtissues currently allows us to decipher disease mechanisms and identify potential therapeutic molecules for cancer patients. However, the histology of these models remains highly inefficient, wasteful, time intensive, and costly as it is difficult to position heterogeneous and complex microtissues for efficient processing. This project aims to address this limitation by the use of acoustofluidics for positioning microtissues within a gel embedding medium. We will develop a device to carry out the positioning of the microtissues as well as an associated labware needed to streamline the process and integrate it within existing histology workflows.
Microtissue processing is highly relevant in basic and applied research and patient care, especially considering the need for personalized therapies in disease treatment. Improving histological analyses will have a positive impact on novel discoveries of disease mechanisms and effective drug molecules.
Job descriptionYour main tasks will center around device development and engineering, prototype testing, characterization, and alignment of microtissues. A collaborative personality and spirit are required in this project that involves internal co-workers as well as co-workers from other disciplines across Switzerland.
Your profileYou should have an engineering background, with an MSc degree, in mechanical, electrical, biomedical engineering, physics, or a related field. Experience in product development and working knowledge of acoustofluidics is preferred but not required.
Your workplace Your workplace We offerchevronright Working, teaching and research at ETH Zurich
We value diversityIn line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.
Curious? So are we.We look forward to receiving your online application with the following documents as a single PDF:
Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
For further information please visit our website. Questions regarding this position should be directed to Dr. Dhananjay Deshmukh ([email protected]) or Prof. Mark Tibbitt ([email protected]) by email (no applications will be accepted by email).
About ETH ZürichETH Zurich is one of the world's leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.
Curious? So are we.We look forward to receiving your online application with the following documents as a single PDF:
Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
For further information please visit our website. Questions regarding this position should be directed to Dr. Dhananjay Deshmukh ([email protected]) or Prof. Mark Tibbitt ([email protected]) by email (no applications will be accepted by email).
Apply online now
About ETH ZürichETH Zurich is one of the world's leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.
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