8 Aug 2023Job Information
University of Trento
Centre for Integrative Biology
Recognised Researcher (R2)
31 Dec 2023 - 23:59 (Europe/Rome)
Type of Contract
Hours Per Week
Offer Starting Date
1 Sep 2023
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
The De Wulf lab at the Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Italy, is looking for an outstanding, highly motivated post-doctoral scientist to study the activity of conserved oncogenic kinase RioK1 in the budding yeast Saccharomyces cerevisiae. The research project wishes to understand how this kinase regulates (peri)centromere transcription activity (by RNA polymerase II), silencing (by Sir histone deacetylases), and transcript turnover (by various RNA processing activities) in order to ensure (1) timely centromeric nucleosome formation, (2) correct kinetochore assembly, and (3) faithful chromosome segregation.
For publications related to the topic, see: Bock LJ et al (2012) Nature Cell Biology, Iacovella MG et al (2015) Nature Communications; Iacovella MG et al (2018) Nucleic Acids Research; Berto G et al (2019) Current Genetics; Juriková K et al. (2021) Trends in Genetics; Smurova K et al (2023) Nature Communications.
Please visit our website for more information on the lab's research, and publications: https:// www. cibio.unitn.it/510/chromosome-segregation-biology
The offer is a 1-year pre-doctoral research contract, that can be further extended after the first 1-year evaluation.Requirements
Biological sciences » Biology
PhD or equivalent
The candidate should hold a recent Ph.D. degree. S/he must be motivated to excel in science, be curious, creative, open-minded, and proactive. The University of Trento (https: // www. unitn.it/) is top-ranked in Italy, and our department (comprising 44 labs, https: // www. cibio.unitn.it/) ranks first in the biological sciences in Italy (awarded with the governmental distinction of "National Department of Excellence"). The daily working languages are Italian and English. The department is very international as for its faculty, students, researchers, management, and administration.
Candidates with some expertise in yeast genetics (strain crossing and tetrad dissection, cellular transformation), biochemistry (protein purifications), cell biology (growing yeast, making yeast cell extracts), and/or molecular biology (RNA isolation, cDNA production, western blot, PCR, RT-qPCR, cloning) are encouraged to apply. Experience with live-cell fluorescence microscopy is much appreciated!
Please send a detailed CV to [email protected]
Years of Research Experience
1 - 4
How to apply : Please send a motivation letter, CV with publications, and the names and emails of 2-3 referees to Peter De Wulf ([email protected]). The University of Trento offers at first a 1-year contract, which can be renewed for up to 3 years. The salary is according to the University of Trento pay scale.
The university is located in the city of Trento (120.000 inhabitants, https: // www. discovertrento.it/), which lies near 300 lakes (including Lakes Garda, Molveno, Levico, etc.), wild-water rivers, and the Dolomite mountains (UNESCO heritage site) allowing for world-class hiking, rock-climbing, cycling and mountain biking, skiing, windsurfing, sailing and parasailing, rafting, etc. (https: // www. visittrentino.info/en, https: // www. trentino.com/en/) and lies near the beautiful cities of Bolzano, Verona, Venice, and Milano.Work Location(s)
Number of offers available
University of Trento, Dept. of Cellular, Computational and Integrative Biology
via Sommarive 9
GeofieldWhere to apply
https:// www. cibio.unitn.it/510/chromosome-segregation-biology
via Sommarive 9