PhD student in Neurochemistry (A)

Stockholm University
September 21, 2022
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atthe Department of Biochemistry and Biophysics. Closing date: 21 September 2022.

The Department is mainly located with the other Departments of Chemistry and Life Sciences in the Arrhenius Laboratories for Natural Sciences, which are situated in the northern part of the University Campus at Frescati. Some 300 people of which about 70 are PhD students work at the Department, engaged in internationally highly recognized research covering a broad range of subjects.

Project description Your studies in Neurochemistry will be in the project "Network Organization and Adaptability of Neurons that Control Innate Behaviours".

The Broberger laboratory at DBB studies the properties and organization of neurons within the neuroendocrine system and that control innate behavior. In recent years, we have demonstrated the electrical behavior of hypothalamic dopamine neurons and their mechanisms and regulation, identified a new population of neurons that control aggression, and addressed how the brain organizes paternal behavior. We approach these issues through a range of techniques, including electrophysiology, imaging of neuronal activity, optogenetics, behavioral paradigms and neuroanatomy, applied in genetically manipulated rodents. This strategy allows us to track behavior down to the properties of individual neurons. We are now looking to recruit a graduate student with a strong background in neuroscience, eager to investigate the functional organization of the brain.

In this project, you will apply electrophysiology to determine the intrinsic membrane properties of hypothalamic neurons, how they connect to each other, and how these features are subject to plasticity as the system adapts to physiological changes and challenges. The system will be studied in organotypic culture and ex vivo brain slices; in vivo recordings may also be included. In addition, anatomical techniques ( e.g. immunofluorescence, in situ hybridization, reconstruction of filled neurons) will be applied to understand the structural substrate of network interactions. Prior experience in the above techniques, especially patch clamp electrophysiology and organotypic cultures of brain tissue, is a strong advantage (please include documentation). Training in the principles of neuronal networks and knowledge of the organization and function of the neuroendocrine system is also a considerable merit. Proficiency in written and spoken English is required.

Qualification requirements In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements for acceptance in Neurochemistry with Molecular Neurobiology program the applicant must have passed courses within the first and second cycles of at least 120 credits in Chemistry/Life Sciences, including at least 15 credits Neurochemistry/Chemistry/Life Sciences at the second cycle level and a Degree Project (Thesis) also in Neurochemistry/Chemistry/Life Science of 30 credits.

Selection The selection among the eligible candidates will be based on their capacity to successfully complete the program. Important criteria when assessing this capacity are: documented knowledge and skill in the field of the thesis project, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews and the candidate's written motivation for seeking the position.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www. su.se/rules and regulations.

Terms of employment Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact For more information, please contact professor Christian Broberger, christian.broberger@dbb.su.se.

General information about the PhD programs can be given by the Director of Doctoral Studies, Pia Ädelroth, pia.adelroth@dbb.su.se, or the Head of the Department, Martin Högbom, martin.hogbom@dbb.su.se.

Union representatives Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, saco@saco.su.se, Alejandra Pizarro Carrasco (Fackförbundet ST/Lärarförbundet), telephone: +46 8 16 34 89, alejandra@st.su.se, seko@seko.su.se (SEKO), and PhD student representative, doktorandombud@sus.su.se.

Application Apply for the PhD student position at Stockholm University's recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the advertisement, and that it is submitted before the deadline.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references
  • and, in addition, please include the following documents

  • Cover letter (1 page) describing: – why you are interested in the field/project described in the advertisement – what makes you suitable for the project in question

  • CV – degrees and other completed courses, work experience and a list of degree projects/theses. Please include relevant experience of techniques.

  • Research proposal (maximum 1 page) outlining a neuroscience question/project that intrigues you and how you would investigate it. (The purpose of this document is not to design the successful candidate's doctoral studies, but to evaluate the scientific thinking of the applicant.)
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (optional; no more than 6 files)
  • Degree projects/theses (optional; no more than 6 files)
  • The instructions for applicants are available at: How to apply for a position.

    You are welcome to apply!

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