Department: DKTK partner site Essen / Düsseldorf - Klinik für Dermatologie
Code number: 2023-0055
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK). At the partner site of DKTK Essen / Düsseldorf the German Cancer Research Center is offering a PhD position for assay development for AHR signature in dermatology.
The PredictAHR project utilizes existing data from the German Cancer Consortium of the tumor entities malignant melanoma, glioma, sarcoma, lung cancer and chronic lymphocytic leukemia and prospectively collects samples that are profiled using high-throughput methods. Our goal is to identify a reduced set of AHR activity markers that are specific to the different tumor entities and allow the development of simple assays for the clinic. Translating the transcriptional AHR signature to proteomics data will enable immunohistochemical evaluation by pathology laboratories, while extension to metabolomics data may enable translation to biological fluids such as blood and urine that can be obtained without surgical intervention. In summary, PredictAHR will investigate the predictive power of the AHR signature in various cancers and develop assays for AHR activity that can be integrated into the clinic.
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ.
Earliest Possible Start Date: as soon as possible
Duration: The position is limited to 3 years with the possibility of prolongation.
Application Deadline: 18.03.2023
Sabine Kaul Phone +49(0)201/723-2044
Please note that we do not accept applications submitted via email.
The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.
Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.
To apply for a position please use our online application portal (https: // www. dkfz.de/en/stellenangebote/index.php).
We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.