PhD Researcher – Effects of BPA replacement products in adipocytes and macrophages (m/f/d)

The Helmholtz-Centre for Environmental Research GmbH – UFZ
March 06, 2023
Offerd Salary:Negotiation
Working address:N/A
Contract Type:Other
Working Time:Negotigation
Working type:N/A
Ref info:N/A

The Helmholtz Centre for Environmental Research (UFZ) with its 1,100 employees has gained an excellent reputation as an international competence centre for environmental sciences. We are part of the largest scientific organisation in Germany, the Helmholtz association. Our mission: Our research seeks to find a balance between social development and the long-term protection of our natural resources.

The job

We are looking for an enthusiastic PhD student to characterize effects of environmental compounds of high concern in adipocytes and macrophages starting on 1st of April or 1st of May 2023. The successful candidate will work in the Department of Molecular Systems Biology investigating molecular interactions and signalling pathways using mass spectrometry-based methods, molecular and cellular techniques. The PhD project is part of the PARC (European Partnership on the Assessment of Risk from Chemicals) project, which aims to increase knowledge on environmental chemicals to improve risk assessment for a better protection of the human health and the environment.

Your tasks
  • Study the effects of novel Bisphenol A replacement products in adipocytes and macrophages using a variety of methods including phenotyping, ELISA, proteomics, single cell proteomics, analysis of post-translational modifications, or protein-interaction studies.
  • Integrate results using bioinformatic approaches to characterize the mode of action of the replacement products.
  • Participate in laboratory group meetings including presentation of results.
  • Carry out collaborative projects with colleagues in the PARC consortium.
  • We offer
  • Excellent technical facilities which are without parallel
  • The freedom you need to bridge the difficult gap between basic research and close to being ready for application
  • Work in inter-disciplinary, multinational teams
  • Excellent links with national and international research networks
  • Excellent support and optimal subject-specific and general training with our HIGRADE graduate school
  • Remuneration in accordance with the TVöD public-sector pay grade 13
  • Your profile
  • M.Sc degree (or near completion) in biochemistry, molecular cell biology or related fields
  • Experience in cell culture of adipocytes and/or macrophages
  • Experience or strong interest in mass spectrometry-based proteomics
  • Interest in toxicological research questions
  • Elevated knowledge in statistics and bioinformatics
  • Excellent English skills
  • Ability to organize and prioritize work efficiently
  • From this employer

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