The Helmholtz Centre for Environmental Research (UFZ) with its 1,100
employees has gained an excellent reputation as an international competence
centre for environmental sciences. We are part of the largest scientific
organisation in Germany, the Helmholtz association. Our mission: Our research
seeks to find a balance between social development and the long-term
protection of our natural resources.
We are looking for an enthusiastic PhD student to characterize effects of
environmental compounds of high concern in adipocytes and macrophages starting
on 1st of April or 1st of May 2023. The successful candidate will work in the
Department of Molecular Systems Biology investigating molecular interactions
and signalling pathways using mass spectrometry-based methods, molecular and
cellular techniques. The PhD project is part of the PARC (European
Partnership on the Assessment of Risk from Chemicals) project, which aims to
increase knowledge on environmental chemicals to improve risk assessment for a
better protection of the human health and the environment.
Study the effects of novel Bisphenol A replacement products in adipocytes
and macrophages using a variety of methods including phenotyping, ELISA,
proteomics, single cell proteomics, analysis of post-translational
modifications, or protein-interaction studies.
Integrate results using bioinformatic approaches to characterize the mode
of action of the replacement products.
Participate in laboratory group meetings including presentation of
Carry out collaborative projects with colleagues in the PARC consortium.
Excellent technical facilities which are without parallel
The freedom you need to bridge the difficult gap between basic research
and close to being ready for application
Work in inter-disciplinary, multinational teams
Excellent links with national and international research networks
Excellent support and optimal subject-specific and general training with
our HIGRADE graduate school
Remuneration in accordance with the TVöD public-sector pay grade 13
M.Sc degree (or near completion) in biochemistry, molecular cell biology
or related fields
Experience in cell culture of adipocytes and/or macrophages
Experience or strong interest in mass spectrometry-based proteomics
Interest in toxicological research questions
Elevated knowledge in statistics and bioinformatics
Excellent English skills
Ability to organize and prioritize work efficiently