Phd Position For An Itn Esr On Epitranscriptomics In The Lab Of Michael Jantsch At The Medical...

Universities and Institutes of Austria
November 15, 2022
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Contract Type:Temporary
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  • Organisation/Company: Medical University of Vienna
  • Research Field: Biological sciences › Biological engineering
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 15/11/2022 00:00 - Europe/Brussels
  • Location: Austria › Vienna
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 40
  • Offer Starting Date: 01/12/2022
  • Eu Research Framework Programme: H2020 / Marie Skłodowska-Curie Actions
  • Marie Curie Grant Agreement Number: 956810
  • The ITN ROPES (ROles of ePitranscriptomic in diseasES) aims at understanding the impact of epitranscriptomic RNA modifcations in disease development. Inosines are introduced in double stranded RNAs by adenosine deaminases acting on RNA. Inosines have been shown to mark endogenous RNAs as "self" to distinguis them from double stranded RNA viruses. Different ADARs exist in mammals that have overlapping functions. Interestingly, only one ADAR isoform is critically required to mark endogenous RNAs as "self". In this project we aim at identifying RNAs and their editing patterns that mark them as "self". We will also aim at developing site directed RNA editing to manipulate endogenous RNA editing events. Technically, we combine mouse genetics with cell biology and molecular techniques including NGS technologies.

    The position is fully funded for two years with the option of extension for up to four years.

    Benefits

    Two years of fully financed PhD position

    Eligibility criteria

    Completed Masters degree. Applicant must not have lived in Austria for more than 12 months during the past four years.

    Selection process

    Applications will be selected by a panel of University members and members from the ITN network ROPES. This will be a two step selection. In the first step written applications will be selected for eligibility. In a second step a personal interview will be conducted.

    Required Research Experiences
  • RESEARCH FIELD
  • Biological sciences

  • YEARS OF RESEARCH EXPERIENCE
  • 1 - 4

    Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Biological sciences: Master Degree or equivalent

  • REQUIRED LANGUAGES
  • ENGLISH: Good

    Skills/Qualifications

    Completed masters thesis in molecular biology, biochemistry, cell biology or a related field.

    Specific Requirements

    Standard Molecular Biology laboratory skills, basik knowledge of statistics, work with cell culture and mice is of advantage.

    Experience with RNA-related work would be of advantage.

    Contact Information
  • Organisation/Company: Medical University of Vienna
  • Department: Division of Cell and Developmental Biology - Jantsch
  • Organisation Type: Higher Education Institute
  • Website: https: // anatomieundzellbiologie.meduniwien.ac.at/group- jantsch/
  • E-Mail: Michael.Jantsch@meduniwien.ac.at
  • Country: Austria
  • City: Vienn
  • State/Province: Austria
  • Postal Code: 1090
  • Street: Schwarzspanierstrasse 17
  • Phone: +43 1 40160 37510
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