The Institute of Analytical Sciences and Physico-Chemistry for Environment and Materials IPREM-UPPA-CNRS (UMR 5254) localized in Pau in collaboration with the Conditions Extrêmes et Matériaux : Haute Température et Irradiation laboratory CEMHTI - CNRS (UPR 3079) located in Orléans (France), opens a PhD position in the frame of the BABE project (Bacterial biofilm control on materials by tuning elasticity, hydration, mobility & charge) granted by the French National research agency (ANR). The PhD project will take place within the cluster 'Physico-chemistry of surfaces and polymer materials' under the supervision of Corinne Nardin at IPREM in Pau and in the team "Nano and Functional Materials: from synthesis to applications" belonging NÒaFMAT of the CEMHTI laboratory under the supervision of Lavinia Balan.
IPREM counts about 350 members interested in the development of fundamental knowledge in physico-chemistry, analytical chemistry and microbiology, in relation to applications concerning the structure of the living, the management of the environment and the functional properties of different classes of materials. The CEMHTI develops expertise and original tools at national and international levels to study in situ the physico-chemical properties of materials in extreme conditions. The PhD candidate will be enrolled in the doctoral school of the Université de Pau et des Pays de l'Adour (UPPA) in Pau- IPREM and in Orléans -CEMHTI and will be cosupervised by the two scientific partners of this thesis project.
Expected skills : - Engineer and/or Master in the area of polymer chemistry with sound knowledge in photochemistry, photo physics and materials science. - The candidate will have to demonstrate a real interest for laboratory work in multidisciplinary teams.
The application file is composed of a motivation letter, a detailed CV, which descibes the internship topics and the master transcript, indicating grades and ranking.
The main objective of this project is the preparation and characterization of antimicrobial coatings, without using biocides, on the basis of a novel approach which we will adopt to prevent biofilm formation, which are responsible of biomaterials and medical devices contaminations. Our multiscale approach is based on : (i) Knowing that material properties, such as stiffness, are not in favor of bacterial adhesion and further biofilm growth. (ii) The possibility to hamper fibrils aggregation through interaction with polymers, being these fibrils used by most of the microorganisms to anchor to a material prior to surface colonization. The materials developed in the frame of the opened PhD position will be prepared by a well-established, single stage photoinduced processing. In combination with the anti-pili action of the free chains at the material surface, the stiffness, hydration and the surface charge will be optimized to hamper biofilm formation. The selection of the most efficient combination of material properties, hydrated or not, will be achieved to propose solutions to issues commonly encountered in the biomedical field. The BABE project, funded by the ANR, gathers several academic and industrial partners.Additional comments
Contacts : C. Nardin, professeur UPPA-IPREM-CNRS Pau E-mail : email@example.com; Tél 0033 5 59 40 77 02
L. Balan, directrice de recherche CNRS - CEMHTI Orléans E-mail: firstname.lastname@example.org ; Tél 02 38 25 56 55Web site for additional job details
https: // emploi.cnrs.fr/Offres/Doctorant/UMR5254-SOPPUY-054/Default.aspxRequired Research Experiences
Chemistry › Physical chemistry
Chemistry › Computational chemistry
Chemistry: Master Degree or equivalent
FRENCH: BasicContact Information