PhD Candidate in Bioinformatics

Norwegian University of Science and Technology
March 15, 2023
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The Department of Computer Science has a vacancy for a

PhD Candidate in Bioinformatics This is NTNU

NTNU is a broad-based university with a technical-scientific profile and a focus in professional education. The university is located in three cities with headquarters in Trondheim.

At NTNU, 9,000 employees and 43,000 students work to create knowledge for a better world.

You will find more information about working at NTNU and the application process here.

About the job

For a position as a PhD Candidate, the goal is a completed doctoral education up to an obtained doctoral degree.

The position is one of three PhD positions within the project Personalized treatment of small-cell lung cancer , which is an interdisciplinary project involving oncology, bioinformatics, and materials science. The overall aim of this project is to develop an affordable, cost-effective, and easily implemented diagnostic classification system for small-cell lung cancer (SCLC). This will enable us, among other things, to assess the extent of disease, predict treatment response and disease development including risk of brain metastases, and estimate time to relapse and survival time.

The PhD candidate will focus on bioinformatics analyses of genomic data from SCLC patients, including single omics (single cell transcriptomics, tumor DNA sequencing) and integrative multi-omics analyses to uncover associations with clinically relevant parameters. The position is available at the bioinformatics and gene regulation research group.

Your immediate leader is Professor Pål Sætrom.

Duties of the position

The PhD candidate's main responsibility will be bioinformatics analyses of high throughput genomics data from SCLC patients and patient-derived tissue models, but the position will also involve the following tasks:

  • Participate in developing and updating software tools for analysing and integrating data from single cell RNA sequencing and bulk RNA and DNA sequencing experiments.
  • Identify multi-omics signatures associated with SCLC patient outcomes.
  • Plan and do bioinformatics analyses to provide new insights into SCLC biology.
  • Use established best practices to ensure that project genomics data and analyses software are available and reusable.
  • Manage and curate project genomics data.
  • Interpret, present, and publish results.
  • Required selection criteria
  • You must have a professionally relevant background in bioinformatics, statistics, systems biology or equivalent education.
  • Your education must correspond to a five-year Norwegian degree program, where 120 credits are obtained at master's level.
  • You must have a strong academic background from your previous studies and an average grade from the master's degree program, or equivalent education, which is equal to B or better compared with NTNU's grading scale. If you do not have letter grades from previous studies, you must have an equally good academic basis. If you have a weaker grade background, you may be assessed if you can document that you are particularly suitable for a PhD education.
  • Documented experience with data analysis in R, Python, or similar.
  • Good written and oral English language skills.
  • The appointment is to be made in accordance with Regulations on terms of employment for positions such as postdoctoral fellow, Phd candidate, research assistant and specialist candidate and Regulations concerning the degrees of Philosophiae Doctor (PhD) and Philosodophiae Doctor (PhD) in artistic research national guidelines for appointment as PhD, post doctor and research assistant

    Preferred selection criteria
  • Experience in next-generation sequencing analyses.
  • Experience in transcriptomics analyses.
  • Experience in multi-omics data integration.
  • Experience in biological interpretation of omics results.
  • Training and experience in software development.
  • Training in molecular biology.
  • Personal characteristics
  • Ability to work independently and with scientific, experimental, or technological creativity.
  • Motivated and excellent team player with positive attitude and with high ambitions on behalf of yourself and the group.
  • Inquisitive with ambitions of acquiring new knowledge and skills.
  • Ability to adjust approaches to overcome setbacks or solve challenges.
  • Emphasis will be placed on personal and interpersonal qualities.

    We offer
  • exciting and stimulating tasks in a strong international academic environment
  • an open and inclusive work environment with dedicated colleagues
  • favourable terms in the Norwegian Public Service Pension Fund
  • employee benefits
  • Salary and conditions

    As a PhD candidate (code 1017) you are normally paid from gross NOK 501 200 per annum before tax, depending on qualifications and seniority. From the salary, 2% is deducted as a contribution to the Norwegian Public Service Pension Fund.

    The period of employment is 3 years.

    Appointment to a PhD position requires that you are admitted to the PhD programme in Computer Science within three months of employment, and that you participate in an organized PhD programme during the employment period.

    The engagement is to be made in accordance with the regulations in force concerning State Employees and Civil Servants, and the acts relating to Control of the Export of Strategic Goods, Services and Technology. Candidates who by assessment of the application and attachment are seen to conflict with the criteria in the latter law will be prohibited from recruitment to NTNU.

    After the appointment you must assume that there may be changes in the area of work.

    It is a prerequisite you can be present at and accessible to the institution daily.

    About the application

    The application and supporting documentation to be used as the basis for the assessment must be in English.

    Publications and other scientific work must follow the application. Please note that applications are only evaluated based on the information available on the application deadline. You should ensure that your application shows clearly how your skills and experience meet the criteria which are set out above.

    The application must include:

  • A cover letter summarizing your research interests, accomplishments, and motivation for applying to this position.
  • CV, certificates and diplomas.
  • Transcripts and diplomas for bachelor's and master's degrees.
  • Name and contact information of two referees.
  • If all, or parts, of your education has been taken abroad, we also ask you to attach documentation of the scope and quality of your entire education, both bachelor's and master's education, in addition to other higher education. Description of the documentation required can be found here. If you already have a statement from NOKUT, please attach this as well.

    We will take joint work into account. If it is difficult to identify your efforts in the joint work, you must enclose a short description of your participation.

    In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience and personal and interpersonal qualities. Motivation, ambitions, and potential will also count in the assessment of the candidates.

    NTNU is committed to following evaluation criteria for research quality according to The San Francisco Declaration on Research Assessment - DORA.

    General information

    Working at NTNU

    NTNU believes that inclusion and diversity is our strength. We want to recruit people with different competencies, educational backgrounds, life experiences and perspectives to contribute to solving our social responsibilities within education and research. We will facilitate for our employees' needs.

    The city of Trondheim is a modern European city with a rich cultural scene. Trondheim is the innovation capital of Norway with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality.

    As an employee at NTNU, you must at all times adhere to the changes that the development in the subject entails and the organizational changes that are adopted.

    A public list of applicants with name, age, job title and municipality of residence is prepared after the application deadline. If you want to reserve yourself from entry on the public applicant list, this must be justified. Assessment will be made in accordance with current legislation. You will be notified if the reservation is not accepted.

    If you have any questions about the position, please contact Professor Pål Sætrom, email: [email protected] If you have any questions about the recruitment process, please contact HR at the Department, e-mail: [email protected]

    If you think this looks interesting and in line with your qualifications, please submit your application electronically via jobbnorge.no with your CV, diplomas and certificates attached. Applications submitted elsewhere will not be considered. Upon request, you must be able to obtain certified copies of your documentation.

    Application deadline: 15.03.23

    NTNU - knowledge for a better world

    NTNU - knowledge for a better world

    The Norwegian University of Science and Technology (NTNU) creates knowledge for a better world and solutions that can change everyday life.

    Department of Computer Science

    We are the leading academic IT environment in Norway, and offer a wide range of theoretical and applied IT programmes of study at all levels. Our subject areas include hardware, algorithms, visual computing, AI, databases, software engineering, information systems, learning technology, HCI, CSCW, IT operations and applied data processing. The Department has groups in both Trondheim and Gjøvik. The Department of Computer Science is one of seven departments in the Faculty of Information Technology and Electrical Engineering .

    Deadline

    15th March 2023

    Employer

    NTNU - Norwegian University of Science and Technology

    Municipality

    Trondheim

    Scope

    Fulltime (1 positions) Fulltime (%)

    Duration

    Temporary

    Place of service

    NTNU Trondheim

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