PhD candidate (f/m/x) in Systems Medicine

January 15, 2023
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Offerd Salary:Negotiation
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Working Time:Full time
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The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www. dzne.de

PhD candidate (f/m/x) in Systems Medicine Code: 1162/2022/12

The clinical single-cell genomics unit at the Systems Medicine DZNE department in Bonn is recruiting n. 2 PhD candidates in the ambit of the European Horizon 2021-2027 project NEUROCOV - The pandemic within: tackling brain vulnerability in COVID-19 at high resolution.

We are a diverse and multidisciplinary team engaged in tailoring systems-level approaches to tackle health and disease questions in the context of precision immunology and neurodegeneration. As leading partners of the NEUROCOV project consortium, we aim to investigate the yet unknown neurological and neuropsychiatric complications which follow COVID-19 infections in clinical cohorts exploiting powerful omics-based, molecular and computational tools. With this study, we want to achieve a high-resolution modeling of the disease dynamics to further stratify patient responses and vulnerabilities, up to the identification of new potential therapeutic options.

For more information, please refer to our Systems Medicine and NEUROCOV project websites.

https: // www. dzne.de/en/research/research-areas/systems-medicine/

https: // www. neurocov.eu/

Your tasks

The successful candidates will employ single-cell multiomics approaches to investigate the immune mechanisms underlying NeuroCOVID in our clinical cohort, working with cutting-edge experimental and computational platforms in a stimulating international environment. The candidates will be coached on how to address biological questions from an experimental and bioinformatic perspective, and will need to acquire skills and knowledge for the independent development of a complete and mature scientific mindset in the field of systems medicine.

Requirements
  • Master or equivalent in immunology, biomedicine, computational biology, or comparable topics
  • Wet-lab experience in molecular biology, possibly in transcriptomics or/and
  • Prior experience in bioinformatic analysis and programming (R, Python)
  • Enthusiastic learning and collaborative working attitude is a must!
  • Very good English communication and writing skills
  • We offer
  • a stimulating high-level research project
  • excellent scientific infrastructure and state-of-the-art methodologies
  • a thriving interdisciplinary research environment at the Bonn DZNE site
  • fully established genomics, bioinformatics and wet-lab facilities
  • modular high-performance computing resources
  • international and cross-sectional network opportunities with the other NEUROCOV European partner groups
  • membership in one of our graduate school programs
  • the position is initially limited to three years with potential for extension.
  • employment, payment, and social benefits are consistent with those at other research institutes
  • If you are interested in this offer, please submit your application online via the link below as a single pdf file, including your CV (incl. two references) and a brief cover letter (max. 1 page) stating your motivation for and prior experience relating to this offer.

    If you have further questions, please contact caterina.carraro@dzne.de. Interviews will take place by video conference, with a possible on-site visit to Bonn. The position is available starting from April (exact date can be further planned) and applications will be considered until the position is filled.

    Site

    Bonn

    Contact details

    caterina.carraro@dzne.de.

    Working hours

    full-time

    Contract length

    3 years, extension possible

    Payment, social benefits

    consistent with those at other research institutes

    Application deadline

    January 15th, 2023

    The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply. We would like to point out that as an employee (f/m/x) of the DZNE Bonn, you are subject to facility-related compulsory vaccination against the COVID-19 virus (according to § 20a of the Infection Protection Act).

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