in DNA Repair
Are you a rising star in the field of structural mass spectrometry (MS)? Would you like to contribute to the development of cutting-edge native MS, hydrogen-deuterium exchange (HDX) and other MS technology and apply it to analysis of nucleic-acid:protein interactions and the study of DNA repair complexes? Do you want to further your career and attain a PhD in one of the UK's leading research-intensive Universities?
You will join the recently funded European Doctoral Network (DN) RepState: DNA Repair State Machines (https: // www. repstate.eu/). RepState offers high- level doctoral training to 13 Doctoral Researchers (DRs) in six different countries. DRs will be supervised by researchers across the network, will be exposed to different sectors via planned placements, attend summer schools, and contribute to and organise workshops and conferences. You will be funded for 3 years and will pursue a doctoral degree during this time.
This DR position is based in the University of Leeds and concerns the investigation of key protein complexes involved in DNA repair using structural MS. In particular, the project involves application of methods such as native MS, ion mobility, HDX-MS, covalent labelling approaches and chemical crosslinking to study conformations of DNA repair state machines such as the UvrD:RNAP and UvrD:MutL complexes. In addition, it will allow the researcher to pioneer new MS approaches to DNA structural biology. This project will be supervised by Prof Sobott, in collaboration with several other researchers across the network.
Important eligibility rules for this position:
There are no restrictions on the nationality, but:
Salary:
To explore the post further or for any queries you may have, please contact:
Frank Sobott, Chair in Biomolecular Mass Spectrometry
Tel: +44 (0)113 343 2576 Email: [email protected]
Location: Leeds - Main CampusFaculty/Service: Faculty of Biological Sciences School/Institute: School of Molecular & Cellular Biology / Astbury Centre for Structural Molecular Biology Category: Research Grade: Off grading structure Salary: £48,640 p.a. plus family allowance, dependent on eligibility in line with Marie Skłodowska-Curie Doctoral Network Working Time: 100% - We are open to discussing flexible working arrangements. Post Type: Full Time Contract Type: Fixed Term (for 3 years due to external funding) Release Date: Friday 02 June 2023 Closing Date: Friday 30 June 2023 Reference: FBSAS1061 Downloads: Candidate Brief
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