The thesis will be realized within the unit « Molecular, Macromolecular chemistry and Materials » (C3M, UMR 7167) at ESPCI Paris. L'École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris) is a famous engineer school (french « grandes écoles »combining high-level research, innovation and pluridisciplinary education. The C3M unit is organized in three teams focusing respectively on molecular chemistry, synthesis and characterization of macromolecules, formulation physico-chemistry. The PhD student will belong to the molecular chemistry and catalysis team. The main research areas of this team concern metal catalysis, photocatalysis, photochemistry and the synthesis of pharmaceutically relevant molecules. The PhD will be supervised by A. Guérinot, assistant professor at ESPCI Paris. Her research work are mainly dedicated to sustainable chemistry with a special focus on earth-abundant metal (photo)-catalysis. The PhD student will belong to doctoral school ED 406 – Molecular chemistry of Paris Centre. The thematics of this doctoral school revolve around molecular chemistry including organic synthesis, catalysis, sustainable chemistry and photocatalysis.
The objective of this PhD project is to develop alternative visible light- induced decarboxylative reactions based on earth-abundant iron photocatalysts allowing the conversion of simple carboxylic acids into attractive compounds. The success of the project will be based on an original combinatorial approach for the photocatalyst (metal/ligand) selection through the simultaneous recording of multiple absorbance spectra, the measurements of redox potentials and the synthesis of a molecular probe. Several decarboxylative reactions will be optimized for the synthesis of valuable building blocks or the late-stage functionalization of complex molecules. Mechanistic studies of the developed transformations will be conducted.Additional comments
A master degree and/or an engineer diploma are required as well as an experimental experience in organic synthesis are required. A solid background in organic chemistry both from a theoretical and experimental points of view is needed. An additionnal experience in photocatalysis will be an asset. The candidate should have a good ability to communicate and patrticularly to write reports and present his/her results in a concise and clear fashion. He will have to be able to conduct his/her project with a good degree of autonomy et will have to be able to work in team.
The applications must include a CV, an application letter, a recommendation letter written by a supervisor of an internship > 3 months, marks of M1 and M2 (or equivalent), a short summary (1 page) of the M2 internship (or equivalent). Applications must be sent on the dedicated portail and not directly to the supervisor.Web site for additional job details
https: // emploi.cnrs.fr/Offres/Doctorant/UMR7167-AMAGUE-002/Default.aspxRequired Research Experiences
Chemistry: Master Degree or equivalent
Environmental science: Master Degree or equivalent
FRENCH: BasicContact Information