Horizon-Msca-2021-Dn-01. Phd Position No. Esr9. Nanoremedi-Phd Programme In Functional Nano-...

Universities and Institutes of Italy
October 28, 2022
Offerd Salary:€ 3311,60
Working address:N/A
Contract Type:Temporary
Working Time:Full time
Working type:N/A
Job Ref.:N/A
  • Organisation/Company: University of Pavia
  • Research Field: Chemistry › Organic chemistry Pharmacological sciences Technology
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 27/11/2022 17:00 - Europe/Brussels
  • Location: Italy › Pavia
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 40
  • Eu Research Framework Programme: HE / MSCA
  • Reference Number: 101072645 — NANOREMEDI
  • Marie Curie Grant Agreement Number: 101072645
  • Marie Skłodowska-Curie Doctoral Network NANOREMEDI-programme in “Functional Nano-Scaffolds for Regenerative Medicine” stems from six Doctoral Courses/Schools at six beneficiary institutions, providing research and training in the field of nanomaterials for Regenerative Medicine. An active contribution of enterprises in training activities is a relevant feature of the programme.

    Beneficiaries (Doctorate Courses/Schools): University of Milan (Pharmaceutical Sciences), ITALY – Coordinating University; Universitat Politècnica de Catalunya (Polymers and Biopolymers) SPAIN; The Hebrew University Jerusalem (School of Chemistry), ISRAEL; Université de Montpellier (Balard Chemical Sciences doctoral school), FRANCE; University of Pavia (Bioengineering, Bioinformatics & Health Technologies), ITALY; IC nanoGUNE (Materials Physics; delivered by University of the Basque Country - Associated Partner linked to NANOGUNE beneficiary), SPAIN.

    Associated partners for secondments activities: Bayer Health Care Pharmaceuticals – ITALY; Edelweiss Connect GMBH – SWITZERLAND; Italfarmaco S.p.A. (CHEMI) – ITALY; Jacobacci & Partners – ITALY; Lynxter -FRANCE; Simune Atomistics SL – SPAIN; Ponti & Partners, SLP – SPAIN; AbMedica – ITALY; DeLama – ITALY; Officine Innovazione Srl (Deloitte) – ITALY; Genepep – FRANCE; BioBasic Europe rsl - ITALY

    The scientific approach proposed by NanoReMedi Consortium is strongly multidisciplinary and will involve a number of different state-of-the-art technologies and methodologies. Expected results are:

  • Generate tissue engineered vascular grafts (VGs) to replace damaged peripheral arteries
  • Study stem-cell based regenerative medicine for bone and cartilage repair
  • Tackle implantation failure of engineered tissues/scaffolds
  • 13 ESR PhD positions are offered by the Consortium related to different and multidisciplinary projects strongly interconnected involving different state- of-the-art technologies and methodologies: Computational chemistry; Chemical synthesis/peptide synthesis; Peptide based Nanomaterials (Soft materials/Hydrogels/Electrospinning) preparation and spectroscopic characterization; Production of vein graph; 3D-tissue fabrication; Biofilm prevention; Electrostimulated release of antimicrobial peptides

    Each ESR will attend the following training activities: i) advanced courses and soft and transferable skill courses provided by University's doctorate courses/schools; ii) multidisciplinary courses/Summer delivered by NanoReMedi Network at the general Network Meetings/; iii) Nine-months secondment at one of the Beneficiary jointly awarding the doctoral degree to improve research methods complementary to those at home institution; iv) Three-months secondment at one of the enterprise where ESRs are expected to acquire complementary skills.

    Job Summary (Fabrication of off-the-shelf biodegradable small calibre vascular grafts (VGs) with improved microbiological and regenerative features)

    1. Testing fibres formation by electrospinning of: i) DOPA-Phe-Phe-RGD; ii) selected newly-synthetized peptides functionalized with DOPAPhe-Phe-RGD and fluorinated AAs. 2. Evaluation of the contribution of compatible adjuvant polymers (i.e. PLA or PLA-PCL) to DOPA-Phe-Phe-RGD-/fluorinated AAs-peptides derivatives on fibres formation. 3. Bi/multi-layered composite flat scaffolds preparation by eletrospinning. 4. Morphological, mechanical, biological and microbiological characterization of the composite flat grafts. 5. Composite small calibre VGs preparation and their morphological, mechanical, physical- chemical and biological characterization. Stability and sterilization studies will be also performed.

    One position is available at University of Pavia in research project ESR9:

    Secondments: i) nine months at The Hebrew University Jerusalem (School of Chemistry, ISRAEL): Microbiological tests on electro-spun flat grafts for evaluating the PBC efficacy to prevent bacterial contamination; ii) three months of enterprise secondment at De Lama S.p.A. (ITALY): to gain specific expertise on sterilization with Hydrogen Peroxide under deep vacuum and zero air.


    Each ESR will receive a 36-month grant to cover his/her participation costs, living, travel and installation allowance, family allowance, as follows:

    Living allowance

    € 3311,60/month

    Mobility allowance

    € 600,00/month

    Family allowance

    € 495,00/month

    Total grant (36 months)

    € 158.637,60

    This amount varies because of the application of a correction coefficient to the living allowance of the country in which the researcher will be recruited.

    The cost of the PhD educational activities, as well as all expenses related to travels performed to attend schools, workshops, and network-organized events, will be planned and sustained by the network through the HORIZON EUROPE MSCA- DOCTORAL NETWORK grant (Institutional Costs).

    The ESR will be provided with office space and all facilities for his/her research program.

    Eligibility criteria
  • Admission to the programme is open to applicants who hold a 2nd Level Master Degree (120 ECTS + 180 ECTS in a bachelor degree) or a Single Cycle Degree (minimum 300 ECTS), or a comparable university degree (Second Cycle qualification), as required by the partner universities for admission to doctoral studies. Applicants are expected to achieve their degree within November 28th, 2022. They shall submit a certified copy of any degree achieved by the deadline of January 31st, 2023.
  • Requirements set by the Consortium concern master's degree (or equivalent) graduates in the fields of computational chemistry, organic chemistry, materials chemistry, materials engineering, chemical engineering, pharmaceutical chemistry, pharmacy, biotechnology, biomedical engineering.
  • Applicants are required to be proficient in the English language (at least B2 level).
  • Applicants should – at the time of recruitment – be in the first four years (full time equivalent research experience) of their research careers not yet have been awarded a doctorate. They must not have resided or carried out their main activity (work, studies, etc.) in the country of their host organization for more than 12 months in the 3 years immediately before their recruitment date. Compulsory national service and/or short stays such as holidays and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account.
  • The Recruitment board will pay special attention to respect gender balance.

    Selection process

    Selection process

    The ESR will be selected on the basis of the following criteria (in random order):

  • scientific skills and research experience;
  • ability to collaborate and communicate;
  • career profile and potential for excellence;
  • expected impact of the proposed training on their career;
  • research project.
  • Additional comments

    Applications must be submitted on www. nanoremedi.eu/APPLICATION by October 28th, 2022 at 17:00 central European time (https:// www. timeanddate.com/time/zones/cet) within November 27th 2022 at 17:00 central European time.

    Applicants are required to submit the following documents by uploading them as a PDF file along with (or as one PDF attachment to) the application form. Instructions on submission are provided on www. nanoremedi.eu/APPLICATION. For more information you may also contact nanoremedi@nanoremedi.eu

    Hand written applications and applications sent by email, post or fax will not be accepted.

    Web site for additional job details

    https: // www. nanoremedi.eu/research-topics/

    Offer Requirements
  • Chemistry: Master Degree or equivalent

    Other: Master Degree or equivalent

    Skills/Qualifications Research field Pharmaceutical Technology - Sub Research Field: Tissue-

    engineering / Regenerative medicine, Material Chemistry, Microbiology

    Required Research Experience - Experimental thesis and/or 1 year

    experience in lab

    Specific Requirements

    Required Education Level 2nd Level Master Degree or Skills/Qualifications 2nd Level Master Degree (120 ECTS + 180 ECTS in a bachelor degree) or a Single Cycle Degree (minimum 300 ECTS), or a comparable university degree (Second Cycle qualification)

    Specific Requirements - Master Degree or equivalent in

    Chemistry/Pharmaceutical Chemistry, Pharmacy, Pharmaceutical Biotechnology

    Required Languages - ENGLISH Required Research Experience - Experimental thesis and/or 1 year

    experience in lab

    Contact Information
  • Organisation/Company: University of Pavia
  • Department: Department of Drug Sciences
  • Organisation Type: Higher Education Institute
  • Website: https: // scienzedelfarmaco.dip.unipv.it/it
  • E-Mail: ida.genta@unipv.it
  • Country: Italy
  • City: Pavia
  • State/Province: None Selected
  • Postal Code: 27100
  • Street: V.le Taramelli 12
  • Phone: (+39) 0382 987371
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