3 PhD Candidates in Molecular Inflammation

Norwegian University of Science and Technology
February 28, 2023
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The Centre of Exellence in Molecular Inflammation Research at The Department of Clinical and Molecular Medicine at NTNU has a vacancy for

3 PhD Candidates in Molecular Inflammation About the positions

3 PhD positions are available in the research groups of prof. Trude Helen Flo and prof. Terje Espevik at the Centre of Excellence in Molecular Inflammation Research (CEMIR), NTNU, Trondheim, Norway. The Flo group seeks to understand how early cellular responses to pathogens are initiated and regulated in space and time, and how this shape infection outcome. We have a particular interest in the cellular host responses to bacterial- and viral pathogens, including Mycobacterium tuberculosis, and we are setting up human stem-cell-based model systems to study how cellular crosstalk regulates inflammation, cell death and the infection outcome. The Espevik group is focusing on functions of the complement system, inflammasomes and Toll-like receptors in relation to intracellular signals induced by microbes and cholesterol crystals. The aim is to find new targets and strategies for regulating immune responses that may result in new therapeutics for treating pathological inflammation.

The PhD candidates will work on projects based in one of the two groups, or on a joint project between the groups. We are looking for highly motivated PhD candidates with some experience in working with stem-cell based models, CRISPR-based gene editing, microscopy, biochemistry, or innate immunity, and who are interested in studying inflammatory responses and cell death.

For a position as a PhD Candidate, the goal is a completed doctoral education up to an obtained doctoral degree.

Your immediate leaders are profs. Trude Helen Flo and Terje Espevik

Key responsibilities

These include but are not limited to:

  • Developing a hypothesis into a tractable research question and experimentally test it
  • Assembling the tools, reagents and know-how required to complete the research project
  • Staying on the top of relevant literature in the field
  • Presenting results from the project and drafting paper(s)
  • Required selection criteria
  • You must have a professionally relevant background in cell biology, biochemistry, molecular biology, immunology or equivalent, including laboratory experience
  • Your education must correspond to a five-year Norwegian degree program, where 120 credits are obtained at master's level
  • You must have a strong academic background from your previous studies and an average grade from the master's degree program, or equivalent education, which is equal to B or better compared with NTNU's grading scale. If you do not have letter grades from previous studies, you must have an equally good academic basis. If you have a weaker grade background, you may be assessed if you can document that you are particularly suitable for a PhD education.
  • Master's students are encouraged to apply, but the master's degree must be obtained and documented before August 1, 2023.
  • You must meet the requirements for admission to the Faculty of Medicine and Health Sciences PhD program in Medicine and Health Sciences https: // www. ntnu.edu/studies/phmedhv
  • Good oral and written communication skills in English
  • The appointment is to be made in accordance with Regulations concerning the degrees of Philosophiae Doctor (PhD) and Philosodophiae Doctor (PhD) in artistic research national guidelines for appointment as PhD, post doctor and research assistant

    Preferred selection criteria
  • Experience in research with CRISPR/Cas9; gene editing and genetic screens
  • Experience in cell systems used to study innate immune responses to infection (signaling, cell death)
  • Experience in microscopy for cell- and sub-cellular studies
  • Personal characteristics
  • Ability to work independently and capable of interacting within a group
  • Sharing, including and honest
  • Ambitious and perseverant
  • Emphasis will be placed on personal and interpersonal qualities.

    We offer
  • exciting and stimulating tasks in a strong international academic environment
  • great research infrastructure and labs in the University Hospital campus, and possibilities for research stay in collaborators lab in Norway or abroad
  • an open and inclusive work environment with dedicated colleagues
  • great opportunities for outdoors activities in nearby nature
  • favourable terms in the Norwegian Public Service Pension Fund
  • employee benefits
  • Salary and conditions

    As a PhD candidate (code 1017) you are normally paid from gross NOK 501 200 per annum before tax, depending on qualifications and seniority. From the salary, 2% is deducted as a contribution to the Norwegian Public Service Pension Fund.

    The period of employment is 3 years.

    Appointment to a PhD position requires that you are admitted to the PhD programme within three months of employment, and that you participate in an organized PhD programme during the employment period.

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    The engagement is to be made in accordance with the regulations in force concerning State Employees and Civil Servants, and the acts relating to Control of the Export of Strategic Goods, Services and Technology. Candidates who by assessment of the application and attachment are seen to conflict with the criteria in the latter law will be prohibited from recruitment to NTNU. After the appointment you must assume that there may be changes in the area of work.

    It is a prerequisite you can be present at and accessible to the institution daily.

    About the application

    The application and supporting documentation to be used as the basis for the assessment must be in English.

    Publications and other scientific work must follow the application. Please note that your application will be considered based solely on information submitted by the application deadline. You must therefore ensure that your application clearly demonstrates how your skills and experience fulfil the criteria specified above.

    The application must include:

  • Motivation letter
  • CV and certificates
  • transcripts and diplomas for bachelor's and master's degrees.
  • A copy of the master's thesis. If you recently have submitted your master's thesis, you can attach a draft of the thesis. Documentation of a completed master's degree must be presented before taking up the position.
  • Name and contact information of three referees
  • Publications or other relevant research work
  • If all, or parts, of your education has been taken abroad, we also ask you to attach documentation of the scope and quality of your entire education, both bachelor's and master's education, in addition to other higher education. Description of the documentation required can be found here. If you already have a statement from NOKUT, please attach this as well.

    We will take joint work into account. If it is difficult to identify your efforts in the joint work, you must enclose a short description of your participation.

    In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience and personal and interpersonal qualities. Motivation, ambitions, and potential will also count in the assessment of the candidates.

    NTNU is committed to following evaluation criteria for research quality according to The San Francisco Declaration on Research Assessment - DORA.

    General information

    Working at NTNU

    NTNU believes that inclusion and diversity is our strength. We want to recruit people with different competencies, educational backgrounds, life experiences and perspectives to contribute to solving our social responsibilities within education and research. We will facilitate for our employees' needs.

    NTNU is working actively to increase the number of women employed in scientific positions and has a number of resources to promote equality.

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    The city of Trondheim is a modern European city with a rich cultural scene. Trondheim is the innovation capital of Norway with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality.

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    As an employee at NTNU, you must at all times adhere to the changes that the development in the subject entails and the organizational changes that are adopted.

    A public list of applicants with name, age, job title and municipality of residence is prepared after the application deadline. If you want to reserve yourself from entry on the public applicant list, this must be justified. Assessment will be made in accordance with current legislation. You will be notified if the reservation is not accepted.

    If you have any questions about the positions, please contact Trude Helen Flo , email trude.flo@ntnu.no. If you have any questions about the recruitment process, please contact Elisabeth Myrvang, e-mail: elisabeth.myrvang@ntnu.no

    If you think this looks interesting and in line with your qualifications, please submit your application electronically via jobbnorge.no with your CV, diplomas and certificates attached. Applications submitted elsewhere will not be considered. Upon request, you must be able to obtain certified copies of your documentation.

    Application deadline: 28.02.2023

    This is NTNU

    NTNU is a broad-based university with a technical-scientific profile and a focus in professional education. The university is located in three cities with headquarters in Trondheim.

    At NTNU, 9,000 employees and 44,000 students work to create knowledge for a better world.

    You will find more information about working at NTNU and the application process here.

    NTNU - knowledge for a better world

    NTNU - knowledge for a better world The Norwegian University of Science and Technology (NTNU) creates knowledge for a better world and solutions that can change everyday life.

    The Faculty of Medicine and Health Sciences (MH) is one of NTNU's largest faculties with about 2000 employees (1300 full-time equivalents).

    The Faculty's main activities are education and research in close integration with St Olav's Hospital. For further information, see: https: // www. ntnu.edu/mh.

    Deadline

    28th February 2023

    Employer

    NTNU - Norwegian University of Science and Technology

    Municipality

    Trondheim

    Scope

    Fulltime (1 positions) Fulltime (%)

    Duration

    Temporary

    Place of service

    From this employer

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