12 Phd Positions In The Msca Doctoral Network Replifate (# Of Pos: 12)

Universities and Institutes of France
January 15, 2023
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Offerd Salary:€40,800
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Contract Type:Temporary
Working Time:Full time
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  • Organisation/Company: Centro de Biología Molecular Severo Ochoa (CBMSO-CSIC)
  • Research Field: Biological sciences › Biology Medical sciences › Other
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 15/01/2023 00:00 - Europe/Brussels
  • Location: Multiple locations, see work locations below.
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 38
  • Eu Research Framework Programme: HE / MSCA
  • Marie Curie Grant Agreement Number: 101072903
  • We are seeking 12 highly motivated fellows eager to pursue a career in science, obtain a PhD abroad and work in one of the three-year research projects we are offering under the the DN- Marie Skłodowska-Curie Actions call of the European Commission. The DN RepliFate focuses on the study of DNA replication, its involvement in cell identity, cancer and inflammation.

    Benefits

    All researchers will be recruited under an employment contract that includes social security coverage.

  • Monthly living allowance : 3,400 euro/month (€40,800/year); this amount is then adjusted through the application of a country correction coefficient to the living allowance of the country in which the researcher is recruited. The country correction coefficients are indicated in Table 1 of the MSCA Work Programme
  • Monthly mobility allowance : 600 euro/month
  • Monthly family allowance , if applicable and depending on the family situation: 660 euro/month.
  • Eligibility criteria

    Fellows will be recruited through an international open call that aims at being “open, efficient, transparent and supportive” as stated in the European Code of Conduct for Recruitment. The process will seek merit-based selection while guaranteeing gender balance, equality, inclusion and transparency in line with the European Charter for Researchers

    If you want to apply for one of our grants you must:

  • Comply with the mobility rule , meaning that they must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date (see below () for exceptions to this rule).
  • Comply with the doctoral candidate criteria , meaning that at the time of recruitment by the hosting institution they have not been awarded a doctoral degree.
  • Fulfil the requirements to be enrolled in a doctoral programme at the hosting institution/country, and, if applicable, the specific eligibility requirements at the hosting institutions.
  • Submit a complete application within the submission deadline through the RepliFate electronic application system.
  • When checking compliance with the mobility rule, the refugee procedure will not be considered as a period of residence in the country where the candidate is applying. When all scores and evaluation criteria are equal, preference will be given to candidates from under-represented groups, for example women, and candidates with disabilities or those from refugee backgrounds.

    Selection process

    We will choose the candidates that fit the most in the different projects in the following steps:

  • Eligibility check : our recruitment committee will check that each application is complete and that applicants fulfil the eligibility criteria described in the previous section.
  • Remote Evaluation : each eligible application will be assessed independently by the principal investigators of our network, according to the project interests indicated by the applicants. The principal investigators will select up to four candidates per position to pass through to the following stage.
  • Online interviews : short-listed candidates will be invited for an online interview. Those who have been positively evaluated but not initially called for interviews will be put on a reserve list. Short- listed candidates will be interviewed by their potential supervisor (i.e. the supervisor responsible for the research project of interest), two additional supervisors from the network, a member of the recruitment committee , and a representative from the associated partners from the non-academic sector.
  • Notification of the selection outcomes : our recruitment committee will notify short-listed candidates of the outcome, and those selected will be put in touch with the corresponding principal investigator and the HR Department of the hosting institution to initiate the hiring procedure.
  • Applicants who have not been successful but who have received a positive evaluation will be put on a waiting list to cover possible renunciations and future positions.
  • Recruitment Calendar

  • Call opening: October 26th
  • Deadline for applications: January 15th
  • Remote evaluation: January 16th – 31st
  • Interviews: February 13th – February 24th
  • Notification to candidates: March 3rd
  • Start date of the fellowship: March – June 2023.
  • Additional comments

    Please apply through our online application system for one to a maximum of two positions and provide the following information (in English):

  • Personal information , such as first name, date of birth, nationality and contact details.
  • Motivation letter (maximum 2 pages) highlighting your research experience and academic achievements and explaining why you are interested in RepliFate and in the selected research projects.
  • Curriculum vitae , including details on education and work experiences.
  • A scanned copy of certified academic records. These documents must show the grades attained in exam periods, when applicable, and evidence that the required degree will be obtained by the expected time of recruitment if it has not already been awarded.
  • Any additional files considered relevant to the application.
  • At least two recommendation letters from university lecturers or scientists who are familiar with your academic work and who can judge your potential as a predoctoral researcher. Applicants will be responsible for ensuring that referees submit these letters.
  • Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Biological sciences: Master Degree or equivalent

    Medical sciences: Master Degree or equivalent

    Skills/Qualifications

    The specific skills and qualifications for each project can be found in the website. The available projects are:

  • Replisome composition as a driver of cell differentiation and malignant transformation.
  • Integrative analyses of DNA replication dynamics, nascent transcription and chromatin conformation changes upon cell.
  • Relevance of FRA3B/FHIT loss in tumorigenesis.
  • Regulation of DNA replication by PTMs during cell fate decisions.
  • Identification of novel ubiquitin/SUMO ligases involved in the DNA damage response/replication stress.
  • Analysis and role of replication features in early mouse embryos and during reprogramming to totipotency.
  • Characterization of immunogenic cytosolic DNA species induced by DNA replication stress (RS).
  • Licensing system aberrations: from replication stress to inflammation.
  • Exploring the genetic space of replication proteins.
  • Discovery of small molecule modulators of human PLK1-Interacting Checkpoint Helicase PICH1 and Ubiquitin-E3LigaseTRIP12.
  • PTM regulation of replication stress responses with implications for ALT and PARPi sensitivity.
  • Role of Interferon and of ISG15 system in DNA replication.
  • Contact Information
  • Organisation/Company: Centro de Biología Molecular Severo Ochoa (CBMSO-CSIC)
  • Department: Genome Dynamics and Function
  • Organisation Type: Public Research Institution
  • Website: https: // www. cbm.uam.es/en/
  • Country: Spain
  • City: Madrid
  • State/Province: Madrid
  • Postal Code: 28049
  • Street: Nicolás Cabrera 1
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